A military source told Syrian state TV that the Air Defense Systems detected hostile and intercepted an "enemy" missile over the central city of Masyaf on Thursday night.
The TV said that an explosion was heard in the sky over Masyaf in the countryside of the central province of Hama.
Citing a military source, SANA reported that at 11:06 pm on Thursday evening the Syrian air defenses were triggered by an "enemy target" flying from northern Lebanon toward Masyaf.
The air defenses intercepted and destroyed the target in mid-air, it added.
Masyaf has repeatedly been attacked by Israeli missiles multiple times in the past.
The Syrian government has repeatedly told that Israel supports the "terror groups" in Syria and its repeated strikes only aim to lift morale of militants.